Within 30–60 Minutes
- Increased focused attention and choice‑reaction time*
- Lowered stress‑induced anxiety and cortisol (stress hormone) within 60 minutes*
The Science Behind PressurePrep
Composure when you need it. Resilience when you build it.
Stress isn’t only a momentary problem. PressurePrep was designed around two goals: support calm, focused attention when pressure is high—and support a more resilient response to everyday stress with consistent use over time.
We started with clinically studied L‑theanine, already widely used in the U.S. for calm, focused attention. Then we searched globally for ingredients with something harder to find: meaningful human clinical evidence for both short‑term composure and longer‑term stress resilience.
That led us to L. gasseri CP2305, a Japanese postbiotic studied for both acute and sustained stress response.
L‑Theanine
39 human research publications
Including 21+ clinical trial reports
L. gasseri CP2305
10 human research publications
Including 9 clinical trial reports and 1 meta‑analysis
Studies cited on this page evaluated the individual ingredients or specific strains—not the finished PressurePrep formula. Individual results may vary.
Why the formula starts in the gut
Your brain really does listen to your gut.
The gut and brain communicate through neural, immune, hormonal, and microbial pathways—often called the gut–brain axis.
That is why PressurePrep includes the postbiotic CP2305: an ingredient studied during both near-term and sustained periods of pressure.*
Two time horizons. Two clinically studied ingredients.
In acute human studies, within 60 minutes L‑theanine improved attention and focus and lowered salivary cortisol, while CP2305 increased alpha‑wave activity and parasympathetic activity and lowered mental‑stress and tension–anxiety scores.*
With consistent daily use in medical students subjected to sustained high pressure over time, CP2305 reduced anxiety and sleep disturbance.*
Studies cited on this page evaluated the individual ingredients or specific strains—not the finished PressurePrep formula. Individual results may vary.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
L‑Theanine
A familiar starting point.
39 Human Research PublicationsL‑theanine is widely used for calm, focused attention without sedation. A recent systematic review and meta‑analysis examined 31 randomized trials involving 1,168 participants across stress, attention and cognitive outcomes.
In acute testing, a single 200 mg dose taken 30–60 minutes before testing significantly improved choice reaction time.*
Stress reduction has also been studied beyond the acute window. A 4‑week randomized trial found significantly lower stress‑related symptom scores and improved sleep quality with daily use, and a separate trial in pharmacy students found lower subjective stress and salivary alpha‑amylase (a marker of sympathetic stress activity) over a multi‑week pharmacy‑practice placement.*
After 4 Weeks
During Pharmacy Practice
- Lower subjective stress and salivary alpha‑amylase (a stress marker) among pharmacy students*
View the research (4 studies)
- Cognitive and affective effects of L‑Theanine: a systematic review and meta-analysis of 31 randomized trials →
- Effects of L‑Theanine Administration on Stress-Related Symptoms and Cognitive Functions in Healthy Adults →
- Randomized, placebo-controlled crossover study of a single 200 mg L‑Theanine dose on stress and salivary cortisol →
- Anti‑stress effect of theanine on students during pharmacy practice: positive correlation among salivary α‑amylase activity, trait anxiety and subjective stress →
But L‑theanine alone wasn’t the product we wanted to build.
*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
L. gasseri CP2305
A different approach to composure—from Japan.
10 Human Research PublicationsCP2305 is a heat‑treated postbiotic that produced measurable changes in brain activity, autonomic activity, and self‑reported stress levels in a randomized human trial.*
Human clinical studies of L. gasseri CP2305 have examined its effects on brain activity, parasympathetic activity and mental‑stress measures after a single dose, and on stress response after daily use for up to 24 weeks.*
Single‑Dose Study
Lower stress, tension, nervousness and unease vs. placebo*
Measured within 60 minutes, during a mental-arithmetic test
Read study →12‑Week, Placebo‑Controlled Study
Helped prevent exam-related cortisol increases*
Daily use in medical students preparing for exams, with improved sleep quality
Read study →24‑Week Study
Lower anxiety scores and improved sleep quality*
Medical students under prolonged examination stress
Read study →*These statements have not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.
Beyond ordinary stress support.
L‑theanine gives PressurePrep a clinically studied, familiar foundation. L. gasseri CP2305 adds an unusual Japanese postbiotic with human research spanning acute and longer‑term stress.
Different ingredients. Different research. One purpose: support greater composure today while building resilience over time.
Today
L‑theanine + L. gasseri CP2305
Calm · Focus · Composure
Consistent Use
L. gasseri CP2305
Everyday stress resilience
What’s actually inside.
Supplement Facts
Amount Per Serving
% Daily Value
Proprietary Synergy Formula
- L‑Theanine†
- Lactobacillus helveticus R0052†
- Bifidobacterium longum R0175†
- Heat-treated L. gasseri CP2305†
† Daily Value not established.
Clinically studied ingredients.
Research is only useful if it helps in real life.
PressurePrep brings together clinically studied ingredients to support calm today and resilience over time.*
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Manufactured in the USA • Made in a GMP‑certified facility • Independently tested